Chemical management software for safer operations

Managing chemicals across sites means keeping SDSs current, tracking changing regulations and knowing which chemicals are approved, where they are used and what risks they pose. SpheraCloud Chemical Management brings chemical data, workflows, reporting and labeling into one system, helping you reduce compliance gaps, improve visibility and keep operations running safely.

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Core capabilities of SpheraCloud Chemical Management

SpheraCloud Chemical Management consolidates supplier safety data sheets (SDSs), chemical inventory information, hazard communication, reporting and chemical approval workflows into one application. Teams can find safety information, understand the substances used across their facilities and apply consistent controls before they order and use new materials. Configurable site structures and permissions support local work while giving authorized users a wider organizational view.

Find and manage SDSs centrally across sites. Sphera’s expert-led indexing ensures 99% chemical data accuracy and reliability, helping you save time and avoid errors

Assign materials and documents by location. Search by material name, CAS number, manufacturer or custom properties, with suggestions and combined queries. Access the latest available SDSs and archived versions to support audits.

Give teams permission-based access through a multilingual browser interface or email. Use a separate offline application to download SDSs, search materials, filter by storage area and access key data.

See what chemicals you have, where they are stored and how they move from receipt to removal. Organize materials by location within a hierarchical site structure so authorized users can maintain assignments, designate responsible contacts and manage protective measures.

Use inventory barcodes in the Chemical Inventory Tracking (CIT) to track individual containers, quantities, storage locations, expiration dates and transactions. Review transaction histories and analyze inventory to understand stock and movement, then export data to Excel for further analysis.

Tailor Sphera’s Chemical Material Approval workflow to your processes. Request new materials or reorders with customized forms and notifications.

Set review steps, responsibilities and required documents across facilities using a drag-and-drop editor. Screen against REACH substances of very high concern (SVHC), California Proposition 65 and your CAS lists. Route results to product stewardship or EHS; request risk assessments or standard operating procedures as needed.

Coordinate stakeholders, including procurement, to complete checks before purchase or use, streamline approvals and maintain audit trails by site or product.

Generate GHS-compliant labels in 34 languages and for multiple jurisdictions for secondary workplace labeling directly from indexed safety data sheet (SDS) data, including chemical identity, hazard pictograms and hazard and precautionary statements.

Access the latest available SDS via QR codes on labels, regardless of the version available when the label was printed. Continue using existing labels when new SDS versions become available, but check whether other labeling changes require reprinting.

Compare SDS ingredients and concentrations with regulatory lists to report on materials, suppliers, CAS numbers, locations, restrictions, SDS revisions, verification, audits and approvals.

Check quantity thresholds and prepare EPCRA 313/TRI and Tier II reporting with Regulatory Threshold Worksheets, the Tier II Wizard and Form R Worksheet. Use appropriate data and expert review to verify results and regulatory applicability.

Ask Sphera AI Agent for Chemical Management Reporting questions in natural language. Get answers based on your own chemical data, refine results through follow-up prompts and export to Excel.

Access over 2.2 million SDSs from more than 10,000 suppliers with SpheraCloud Chemical Management. Index over 250 data points—including composition, classifications across 39 GHS agencies and physical properties—in 249 SDS languages, with 99.5% accuracy and a 48-hour turnaround. Support users with 34 secondary-label languages, plus supplier regular outreach for updated SDSs.

Validate supplier SDS composition and fill missing CAS numbers using SCCM’s library of over 400,000 substances to support accurate regulatory reporting.

Screen facility substances against over 500 regulatory lists worldwide to identify potential obligations and take action.

Assess worker and environmental risks by task, work area and site. Use SDS hazard data in assessment workflows to identify mitigation measures and select consistent controls across locations.

Reassess risks and controls as inventories, regulations, SDS data or operating conditions change. Use reassessment workflows and audit trails to support compliance.

Guide frontline teams toward safer daily work and see chemical risks across sites.

Exchange chemical data with your ERP and other business systems through APIs, reports and exports. Link SAP material numbers to chemical records and manage supplier SDSs alongside those created separately in Sphera Intelligent Authoring. Confirm compatibility with your ERP and EHS platforms, connector availability, update frequency and any chemical supplier database fees before implementation.

Why leaders choose SpheraCloud Chemical Management

Standardize chemical management across sites with SDS data that Sphera experts index, verify and keep current. Built for enterprise-wide implementations on a global scale, with support during and after your implementation. 

Gain visibility across operations

All your sites work on SDS and chemical data they can trust: Sphera’s expert team extracts over 250 data points from each SDS, including composition, physical properties and classifications covering 39 different GHS agencies. Indexing covers 249 SDS languages at 99.5% accuracy. A substance library of more than 400,000 substances validates supplier composition data and fills gaps where CAS numbers are missing.

Lower chemical risk across every site

Route every new chemical through a standard approval workflow before it enters your operations. Each request is checked against more than 500 regulatory lists, so reviewers see hazard and regulatory information before they decide. Approvals are tracked, and noncompliant materials stay out. Once approved, track each chemical from arrival and storage through use and departure. Assess the risk of each chemical using its hazard data, so teams can prioritize where to act.

Save time and reduce costs

Sphera experts index your SDSs with a 48-hour turnaround, so nobody re-keys supplier data by hand. SpheraCloud Chemical Management is available in 34 user interface languages, and secondary labels are created in the same 34 languages, so every site works in its preferred language. Standardized templates and configurable workflows get you up and running quickly, so you see a return sooner.

Stay ahead of regulatory change

More than 500 regulatory lists from around the world, including REACH, RoHS, TSCA and CLP, show which substances in your facilities may carry obligations. You see the risk earlier and can act while documentation is still current.

Built for complex industries

Chemical Manufacturing

Screen ingredients and route material approvals to address substance restrictions before chemicals enter production.

Retail and Consumer Goods

Centralize supplier SDSs and screen restricted ingredients to address chemical requirements across diverse product ranges and store locations.

Automotive

Screen process chemicals against customer restrictions and generate workplace labels to support chemical controls across plants and production lines.

Healthcare

Provide location-specific SDS access and clear workplace labels to help staff handle cleaning, disinfection and laboratory chemicals safely.

Explore the modules
in this suite

Our Chemical Management Software helps businesses control everything from raw materials to final product packaging, supporting precise, predictable and scalable chemical programs for global supply chains and an ever-changing regulatory landscape.

Safety Data Sheet Management Software

Manage, monitor, report and provide universal access to Safety Data Sheets.

Document Storage Software

Organize, share and quickly find internal documents and policies.

Chemical Risk Assessment Software

Assess chemical exposure risks and define safer controls across sites.

Administer, track and manage your materials

Comprehensive chemical management is critical for the safety of your employees and for compliant operations. The more chemicals and hazardous substances you have, the higher the risks of using and storing them. The more countries you ship chemicals to, the greater the complexity of managing regulations effectively from receipt through use and disposal.

2.2
M
SDSs in Sphera repository
10,000
+
unique suppliers
400
K+
substances in substance library
99.5
%
indexing accuracy
 

Is your chemical management inefficient?

The right system can eliminate your fears of noncompliance, wasted resources and inefficiencies. Work smarter, not harder.

 

What to know about SDS verification

Verification is essential for regulatory compliance, and SDSs ensure that people can safely handle, use and distribute the chemicals in the substances they create.

 

Streamlining systems for efficiency

A multinational apparel company sought to consolidate their chemical management processes to improve efficiency and transparency across the organization.

 

Do you know all your chemical risks?

Turn disconnected chemical data into actionable risk insights. Chemical Risk
Assessment helps you understand exposure risks, apply consistent controls across
sites and support safer work and compliance.

Our Awards

Link to be defined

Green Quadrant

Product Compliance Software

2025

Link to be defined
Clip path group

Green Quadrant

EHS Software

2025

Request a demo

Fill out the form and we will get back to you to discuss your Chemical Management Software needs.

Resources

Turn chemical data into safer work

Turn chemical data into safer work

Download the brochure to learn how Sphera helps standardize chemical risk assessments, improve worker safety and support compliance.
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FAQs

Through SpheraCloud, we provide software tools with broad and deep content and a team of experienced professionals to create an optimized approach to product stewardship.

Chemical Management Software helps you manage and monitor chemical inventories, stay compliant with regulations and give your team a central source of information about response plans and other details.

Sphera’s Chemical Management Software goes beyond simply helping you keep track of chemical inventory. We help you consolidate data, stay compliant and create efficiencies.

A chemical management system helps your company stay safe and compliant. It can also help your company improve response times and become more operationally efficient. Sphera’s Chemical Management Software makes chemical management simple and straightforward.

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